Molecular Aspects Of Oxidative Drug Metabolizing Enzymes: Their Significance In Environmental Toxicology, Chemical Carcinogenesis And Health (Nato Asi Subseries H:)
Presented here are recent advances in biochemical, toxicological, and regulatory aspects of oxidative drug metabolizing enzymes. Mainly cytochrome P450-dependent and flavin-containing monooxygenases (FMO) are covered. Moreover, the book deals with genotoxicity studies and toxicological interactions of environmental chemicals and mechanisms of mutagenicity and tumor formation. The construction of g...
Series: Nato ASI Subseries H: (Book 90)
Paperback: 614 pages
Publisher: Springer; Softcover reprint of the original 1st ed. 1995 edition (December 13, 2011)
Product Dimensions: 6.1 x 1.4 x 9.2 inches
Format: PDF ePub fb2 TXT fb2 book
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engineered mammalian cells for the production of a specific P450 isozyme and the application of these cell lines in drug metabolism, mutagenicity and toxicity studies are described in detail. Further, insight is provided into how a number of aquatic species cope with pollutants and their genotoxicity.